

| SHIRE PLC | 22/06/2005 AGM | |
|---|---|---|
| 1 | Receive report and accounts | Abstain |
| 2 | Re-elect Mr Matthew William Emmens | For |
| 3 | Re-elect Mr Ronald Maurice Nordmann | For |
| 4 | Re-elect Dr Barry John Price | For |
| 5 | Re-appoint auditors | Oppose |
| 6 | Fix auditors' remuneration | For |
| 7 | Approve remuneration report | Oppose |
| 8 | Issue shares with pre-emption rights | For |
| 9 | Disapply pre-emption rights | For |
| 10 | Authorise share repurchase | For |
| 11 | Authorise EU political donations and political expenditure | For |