| 1a. | Election of Class I Director of Alnylam to serve for a term ending in 2029: Stuart A. Arbuckle | For |
| 1b. | Election of Class I Director of Alnylam to serve for a term ending in 2029: Yvonne L. Greenstreet, M.D. | For |
| 1c. | Election of Class I Director of Alnylam to serve for a term ending in 2029: Elliott Sigal M.D., Ph.D. | Oppose |
| 2. | Advisory Vote on Executive Compensation | Oppose |
| 3. | To ratify the appointment of PricewaterhouseCoopers LLP, an independent registered public accounting firm, as Alnylam's independent auditors for the fiscal year ending December 31, 2026. | Oppose |
