| 1A | Elect Patrice Bonfiglio as Sarissa Nominee to the Board | Withhold |
| 1B | Elect Alexander Denner as Sarissa Nominee to the Board | Withhold |
| 1C | Elect Sarah J. Schlesinger as Sarissa Nominee to the Board | Withhold |
| 1D | Elect Emily Peterson Alva | Withhold |
| 1E | Elect Cato T. Laurencin | Withhold |
| 1F | Elect Brian P. McKeon | Withhold |
| 1G | Elect Christopher I. Wright | For |
| 1H | Elect Shane M. Cooke | Withhold |
| 1I | Elect Richard B. Gaynor | For |
| 1J | Elect Richard F. Pops | Withhold |
| 2 | Advisory Vote on Executive Compensation | Abstain |
| 3 | Appoint PwC as Auditors | Oppose |
| 4 | Approve Alkermes Plc 2018 Stock Option and Incentive Plan | Oppose |
| 5 | Issue Shares for Cash | Oppose |
| 6 | Authorise the Board to Waive Pre-emptive Rights | Oppose |
