

| ALNYLAM PHARMACEUTICALS INC | 02/05/2017 AGM | |
|---|---|---|
| 1.01 | Re-elect Michael W. Bonney | For |
| 1.02 | Re-elect John M. Maraganore | For |
| 1.03 | Re-elect Paul R. Schimmel | Oppose |
| 1.04 | Re-elect Phillip A. Sharp | Oppose |
| 2 | Approve the Second Amended and Restated 2009 Stock Incentive Plan | Oppose |
| 3 | Approve the Amended and Restated 2004 Employee Stock Purchase Plan | For |
| 4 | Advisory Vote on Executive Compensation | Abstain |
| 5 | Approve the Frequency of Future Advisory Votes on Executive Compensation | 1 |
| 6 | Appoint the Auditors | Oppose |