| 1.1 | Elect Leonard Bell | Withhold |
| 1.2 | Elect David R. Brennan | For |
| 1.3 | Elect M. Michele Burns | For |
| 1.4 | Elect Christopher J. Coughlin | For |
| 1.5 | Elect David L. Hallal | For |
| 1.6 | Elect John T. Mollen | For |
| 1.7 | Elect R. Douglas Norby | Withhold |
| 1.8 | Elect Alvin S. Parven | Withhold |
| 1.9 | Elect Andreas Rummelt | For |
| 1.10 | Elect Ann M. Veneman | Withhold |
| 2 | Advisory vote on executive compensation | Oppose |
| 3 | Appoint the auditors | Oppose |
| 4 | Approval of Alexion's 2015 Employee Stock Purchase Plan | For |
| 5 | Shareholder Resolution: proxy access | For |
| 6 | Shareholder Resolution: give shareholders owning 10% of Alexion's stock the power to call a special meeting | For |