IONIS PHARMACEUTICALS INC. 04/06/2020 AGM
1.1Elect Director Joseph H. WenderWithhold
1.2Elect Director B. Lynne ParshallFor
1.3Elect Director Spencer R. BerthelsenWithhold
1.4Elect Director Joan HernanFor
2Amend Existing Omnibus PlanOppose
3Porposal to ratyfy amending existing stock option and restricted stock unit awards of directors to adjust vesting. For
4Advisory Vote on Executive CompensationOppose
5Appoint the AuditorsOppose