IONIS PHARMACEUTICALS INC. 06/06/2019 AGM
1.1Elect Stanley T. Crooke Withhold
1.2Elect Joseph Klein, IIIWithhold
1.3Elect Joseph LoscalzoFor
1.4Elect Michael HaydenFor
2Elect Peter N. ReikesFor
3Elect Brett Monia Oppose
4Amend Existing Omnibus PlanOppose
5Advisory Vote on Executive CompensationAbstain
6Appoint the AuditorsOppose